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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: tRFAla-AGC-3-M8 attenuates neuroinflammation and neuronal damage in Alzheimer’s disease via the EphA7-ERK1/2-p70S6K signaling pathway

Fig. 3

KEGG and GO enrichment analyses of tRFAla−AGC−3−M8 target genes. (A) KEGG analysis identified the axon guidance pathway as the most significant for the predicted target genes. (B) Pathway-Gene network diagram showing that EphA7 (Universal Protein Resource ID: 13041, labeled with a black box) is involved in the axon guidance pathway. (C) GO analysis revealed synapse organization as the key biological process. (D) Biological Process-Gene Waterfall plot illustrating EphA7's role in synapse-related activities (labeled with a black box)

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Alzheimer's Research & Therapy

ISSN: 1758-9193