Fig. 4

Correlation matrix for mGluR5 and synaptic density (no PVC) of all regions in CN participants

The matrix displays Pearson’s correlation coefficients (r) between [¹⁸F]FPEB (mGluR5) and [¹¹C]UCB-J (synaptic density) PET DVRs for all possible combinations of regions. Data are from 12 cognitively normal participants. The heat map shows the r for all combinations that had an uncorrected p < 0.05. Abbreviations: CN = cognitively normal; DVR = Distribution volume ratios; mGluR5 = metabotropic glutamate receptor subtype 5; PVC = partial volume corrected