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Table 5 Associations of oxysterols with risks of EMCI and LMCI

From: Linking oxysterols and different stages of mild cognitive impairment: insights from gut metabolites and N6-methyladenosine

 

EMCI/CON

LMCI/CON

LMCI/EMCI

Oxysterols

OR

P

OR

P

OR

P

27-OHC

1.272

(1.056, 1.532)

0.011*

1.364

(1.119, 1.663)

0.002*

1.066

(0.913, 1.245)

0.417

24S-OHC

1.132

(1.029, 1.245)

0.011*

1.145

(1.038, 1.264)

0.007*

1.003

(0.921, 1.092)

0.948

27-CA

0.967

(0.931, 1.003)

0.074

0.994

(0.963, 1.026)

0.719

1.023

(0.989, 1.059)

0.182

7-HOCA

1.009

(0.980, 1.038)

0.563

0.999

(0.967, 1.031)

0.929

0.987

(0.953, 1.021)

0.442

  1. Abbreviations: EMCI, early mild cognitive impairment; LMCI, late mild cognitive impairment; OR, odds ratio; 27-OHC, 27-hydroxycholesterol; 24S-OHC, 24S-hydroxycholesterol; 27-CA, 3β-hydroxy-5-cholestenoic acid; 7-HOCA, 7α-hydroxy-3-oxo-4-cholestenoic acid. ∗P < 0.05
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Alzheimer's Research & Therapy

ISSN: 1758-9193