Fig. 1

Heat maps of (a) Unadjusted (lower triangle) and adjusted (partial; upper triangle) correlations between baseline plasma biomarker concentrations, baseline MRI volumetric measures, and baseline scores on the ADAS-Cog11 and CDR-SB, and (b) Unadjusted and adjusted (partial) correlations between baseline or 48-week change of plasma biomarker concentrations, with 48-week change on the ADAS-Cog11, CDR-SB, and MRI volumetric measures. * p < 0.05; ** p < 0.01; *** p < 0.005