Fig. 7

Increased Aβ expression in the DG of Tg2576 mice. (A) Representative micrographs of immunohistochemical labeling of Aβ with the McSA1 antibody (green) and DAPI (blue) in horizontal sections for WT (1) and Tg2576 mice (2). Images show the hilus, granule cell layer (GCL), molecular layer (ML) and CA3. The boxed areas are shown at higher power below. Hilar cells expressing Aβ are shown in green and pointed with arrows. (B) There was significantly more intracellular Aβ labeling with the McSA1 antibody for hilar cells from Tg2576 mice compared to WT