Fig. 2

ROC curve associated with ability of CSF sSorlA levels to predict if a patient is carrier of a trafficking defective SORL1 variant. The ROC curve was obtained by computing sensitivity and specificity associated with different thresholds of CSF sSorlA levels to distinguish between patients in AD SORL1 TD group and patients in AD SORL1 nTD + AD SORL1 WT group