Table 1 EPAD demographics
| Â | Super healthy (baseline) | 'at-risk'(baseline) | 'at-risk'(latest visit) |
|---|---|---|---|
N | 337 | 592 | 592 |
Sex (M:F) | 199:138 | 351:241 | 351:241 |
Mean ± sd Age (years) | 64.0 ± 7.0 | 65.4 ± 7.6 | 65.6 ± 7.6 |
Mean ± sd ICV | 1.50 ± 0.15 | 1.49 ± 0.16 | 1.49 ± 0.16 |
Mean ± sd p-tau pg/mL CSF | 16.7 ± 7.32 | 20.3 ± 9.96 | 20.3 ± 9.34 |
Mean ± sd t-tau pg/mL CSF | 198 ± 74.0 | 231 ± 94.3 | 231 ± 92.2 |
Mean ± sd abeta42 pg/mL CSF | 1555 ± 797.1 | 1310 ± 692.2 | 1353 ± 717.1 |
Mean ± sd CDR global score | 0 | 0.19 ± 0.25 | 0.19 ± 0.25 |
Mean ± sd MMSE total score | 29.6 ± 0.48 | 28.1 ± 1.80 | 28.2 ± 1.77 |
ApoE (0 variants:1 variant:2 variants) | 325:0:0 | 259:252:32 | 272:252:32 |