Fig. 3
From: Fibre density and cross-section associate with hallmark pathology in early Alzheimer’s disease

Voxel-based group comparisons. Clusters of significantly (A) increased amyloid PET, (B) increased tau PET and (C) reduced synaptic density PET in aMCI compared to HC. Colour bars indicating SPM t-values. Thresholds for cluster height and voxel height were PFWE < 0.05 and Puncorrected < 0.001, respectively. aMCI = amnestic mild cognitive impairment; HC = healthy controls; PET = positron emission tomography; SPM = statistical parametric mapping